Tubacin

Product Name: Tubacin
CAS No.: 537049-40-4
Chemical Name: Tubacin
Synonyms: Tubacin;BML-GR362;4R,6S)N8-[(2R,dioxan-Tubacin, >=98%;diphenyl-oxazolyl)
CBNumber: CB32519138
Molecular Formula: C41H43N3O7S
Formula Weight: 721.86
MOL File: 537049-40-4.mol

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Tubacin Property

Melting point:: 155 - 157°C
storage temp.: -20°C
solubility: DMSO: ≥10mg/mL
form: powder
color: white to tan

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0065
Product name: Tubacin
Purity: ≥98% (HPLC)
Packaging: 1mg
Price: $239
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0065
Product name: Tubacin
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $631
Updated: 2024/03/01

Cayman Chemical

Product number: 13691
Product name: Tubacin
Purity: ≥90%
Packaging: 1mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 13691
Product name: Tubacin
Purity: ≥90%
Packaging: 5mg
Price: $336
Updated: 2024/03/01

Tocris

Product number: 3402
Product name: Tubacin
Purity: ≥96%(HPLC)
Packaging: 1
Price: $287
Updated: 2021/12/16

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Tubacin Chemical Properties,Usage,Production

Uses

Tubacin is tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC6).

Definition

ChEBI: N-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide is a member of 1,3-oxazoles.

Biochem/physiol Actions

Tubacin triggers the release of reactive oxygen species and mediates caspase-3-independent apoptosis of Epstein-Barr virus (EBV)-positive Burkitt lymphoma cells. It suppresses the proliferation of acute lymphoblastic leukemia (ALL) cells and enhances the effect of chemotherapy to treat ALL cells. Tubacin prevents the epileptic activity and neuronal migration defects caused due to lowered expression of Srpx2 in rats.

target

HDAC6

Tubacin Preparation Products And Raw materials

Raw materials

Preparation Products

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Tubacin Suppliers

China 69 India 2 United States 13 Global 84

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

537049-40-4, TubacinRelated Search:

1H-Benz[de]isoquinoline-2(3H)-butanamide SCRIPTAID SPLITOMICIN Sodium 4-phenylbutyrate BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE APICIDIN CAY10603 OXAMFLATIN Entinostat HC TOXIN M344 Parthenolide ACY-1215 TRICHOSTATIN A Tacedinaline Nexturastat A Mocetinostat (MGCD0103) Tubastatin-A

Tubacin

N1-(4-((2R,4R,6S)-4-((4,5-diphenyloxazol-2-ylthio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide

N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide Tubacin

N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

Tubacin, >=98%

BML-GR362

N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-di

Tubacin (BML-GR362)

Octanediamide, N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-, rel-

Octanediamide,N-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxy-, rel-

Tubacin (tubulin acetylation inducer)

rel-N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide

Tubacin,Inhibitor,HDAC,Virus Protease,inhibit,Histone deacetylases

(hydroxymethyl)&#8203

[(2R,&#8203

4R,&#8203

6S)&#8203

dioxan-&#8203

diphenyl-&#8203

N8-&#8203

Octanediamide, N1-&#8203

oxazolyl)&#8203

537049-40-4

C41H43N3O7S

Inhibitors